How to Start Buprenorphine (Bup/Suboxone/Subutex) On Your Own

Concurrent Opioid Use Micro-Induction

“Micro-dosing” is a way to start Buprenorphine without getting sick.

How does micro-dosing work?

  • You can start buprenorphine without having to stop using opioids like heroin, methadone, or fentanyl first.
  • Micro-dosing starts buprenorphine slowly so that your body doesn’t feel it.
  • You don’t have to be sick (in withdrawal) to start. You can keep using opioids while you’re getting to the right dose.

How to take our medicines:

  • Keep buprenorphine under your tongue until fully dissolved.
  • Do not eat or drink while it is dissolving.

Time to start:

Use 2mg on days 1-5

an image of how and where to cut medication


Day 1

Morning dose: Take 0.5mg


Day 2

Morning dose: Take 0.5mg
Evening dose: Take 0.5mg


Day 3

Morning dose: Take 1mg
Evening dose: Take 1mg


Day 4

Morning dose: Take 2mg
Evening dose: Take 2mg


Day 5

Morning dose: Take 2mg and 1mg
Evening dose: Take 2mg and 1mg


Days 6-8

Use 8mg on days 6-8

an image of how and where to cut medication


Day 6

Morning dose: Take 4mg
Evening dose: Take 4mg


Day 7

Morning dose: Take 8mg
Evening dose: Take 8mg

    • Stop taking all opioids by the end of the day
    • Start taking comfort medications as prescribed by your provider

Day 8 and onward

Take fully prescribed dose


Take comfort medications if prescribed by your provider.
If you still feel sick, text BLP at (866) 679-0831 for more support.